Human PAI -1 Elastase specific mutant
货号:APAI
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规格:1.0 mg
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价格:¥0.00
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品牌:Molecular Innovations
Human PAI -1 Elastase specific mutant是由北京中昊新生科技有限公司提供,Molecular Innovations专注于凝血和溶栓试剂,包括PAI-18、tPA、尿激酶、凝血因子、玻连蛋白、纤维蛋白原、纤连蛋白、肾素原/肾素、前激肽释放酶、激肽释放酶、白蛋白、纤溶酶原、纤溶酶、抗纤溶酶、凝血酶、抗凝血酶、补体成分和免疫球蛋白。
A single mutation at the P1 position of PAI-1 alters the target specificity of PAI-1 from the plasminogen activators tPA and uPA to elastase. PAI-1 is normally a substrate for pancreatic and neutrophil elastase becoming cleaved at the P3 position. This mutant contains a P1 Alanine in place of the wild type Arginine residue resulting in an inhibitor of elastase as potent as alpha-1PI (antitrypsin).
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