Rat PAI-1 (NBD labeled at the scissile bond of the reactive cent
货号：RPAI-P1NBD
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规格：0.5 mg
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价格：￥0.00
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品牌：Molecular Innovations
Rat PAI-1 (NBD labeled at the scissile bond of the reactive center loop)是由北京中昊新生科技有限公司提供，Molecular Innovations专注于凝血和溶栓试剂，包括PAI-1733、tPA、尿激酶、凝血因子、玻连蛋白、纤维蛋白原、纤连蛋白、肾素原/肾素、前激肽释放酶、激肽释放酶、白蛋白、纤溶酶原、纤溶酶、抗纤溶酶、凝血酶、抗凝血酶、补体成分和免疫球蛋白。
P1'-NBD rat PAI-1 was created by mutagenesis of the methionine residue (Met348) at the P1-P1' scissile bond to cysteine. This provides a free thiol group for labeling with NBD, a fluorescent probe highly sensitive to changes in solvation and hydrophobic environment. The fluorescence emission of P1'-NBD PAI-1 is quenched upon cleavage of the reactive center loop by a target proteinase. This unique product is an ideal reagent for researchers studying PAI-1 behavior in rat models.
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