DNA氧化标志物 DNA oxidation marker
标志物名称 | 指标 | 应用 | 备注 |
---|---|---|---|
8-OHdG | |||
New 8-OHdG Check ELISA Kit (Code. KOG-200SE), ELISA:450nm, 96 wells | Assay range: | Urine,Serum | Suitable for urine and animal serum. Assay time: 2.5 hours.(KOG-200SE) |
Highly Sensitive 8-OHdG Check ELISA Kit | Assay range: 0.125-10 ng/mL | Urine,Serum,Cells | Suitable for human serum,tissue and cultured cells. Assay time: overnight +1.5 hours(KOG-HS10E) Highly specific to 8-OHdG. Low cross reactivity to oxidized RNA(8-OHGua/8-OHG). |
Anti 8-OHdG monoclonal antibody (N45.1) (Code: MOG-020P / MOG-100P) | 20 µg / 100 µg | Cells | |
Anti Thymidine Glycol (TG) antibody (Code: MTG-100P) Clone 2E8 | 100 µg of IgG | Cells | DNA-specific oxidative stress marker. Specific to TG in DNA polymer. |
脂质氧化标志物 | |||
HEL (13HPODE-Lys adduct) | |||
Hexanoyl-Lysine (HEL) ELISA kit (Code: KHL-700E), ELISA: 450nm, 96 wells | Assay range:2 - 700 nmol/L | Urine,Serum,Cells | Nε-Hexanoyl-Lysine (HEL) is derived from 13-HPODE, and is a novel biomarker for early stage oxidation of n:6 polyunsaturated fatty acid. Detectable in urine, serum, tissue and cultured cells. |
Anti Hexanoyl-Lysine (HEL) antibody (Code: MHL-021P) Clone 5F12 | 20 µg of IgG | Cells | |
4-HNE Anti 4-HNE monoclonal antibody (HNEJ2) (Code: MHN-020P / MHN-100P) | 20 µg /100 µg | Cells | 4-hydroxy-2-nonenal (4-HNE) is one of the major oxidized products of fatty acids. Specific to 4-HNE-modified proteins. |
MDA Anti MDA monoclonal antibody (Code: MMD-030n) Clone 1F83 | 30 µg of IgG | Cells | Specific to Malondialdehyde(MDA)-protein adducts such as dihydropyridine-lysine (DHP-lysine). By utilizing 3rd derivative analysis, more reliable results than that by traditional TBARS assay. |
Malondialdehyde assay kit (TBARS) (Code: KMD-008W) Colorimetric: 400-700nm scan | Assay range: | Urine,Serum,Cells | |
Anti Acrolein (ACR) antibody (Code: MAR-020n / MAR-100n) Clone 5F6 | 20 µg /100 µg | Cells | Specific to ACR modified proteins: formyl-dehydropiperidino-lysine (FDP-lysine). |
Anti 4-hydroxy-2-hexenal (4-HHE) antibody (Code: MHH-030n) Clone HHE53 | 30 µg of IgG | Cells | Specific to HHE-histidine Michael adduct (HHE-His). |
Anti Crotonaldehyde (CRA) antibody (Code: MCA-030n) Clone 82D3 | 30 µg of IgG | Cells | Specific to CRA-protein aduucts. |
Anti Methylglyoxal (MG) antibody (Code: MMG-030n) Clone 3C | 30 µg of IgG | Cells | Specific to MG-protein adduct (argpyrimidine). |
Anti 7-ketocholesterol (7-KC) antibody (Code: MKC-020n) Clone 35A | 20 µg of IgG | Cells | Biomarker of cholesterol oxidation. Applicable for frozen tissue only. |