Deoxyribonuclease I，即DNase I，中文名称：脱氧核糖核酸酶I，来源于牛胰腺（bovine pancreas）。

别名：脱氧核糖核酸5′-寡核苷酸-水解酶；Deoxyribonucleate 5′-oligonucleotido-hydrolase。

分子量 ~31 kDa，CAS号 9003-98-9，EINECS编号 232-667-0，EC Number 3.1.21.1，MDL编号 MFCD00130918。

级别：Molecular Biology Grade

Deoxyribonuclease I from bovine pancreas；
Type: Type IV；
Activity…………≥2,000 Kunitz units/mg protein；
Chymotrypsin………………………≤0.5%；
Protease…………………………………≤0.05%；
RNase…………………………………..≤0.02%；
solubility………0.15 M NaCl: soluble 5.0 mg/mL。

脱氧核糖核酸酶I(Deoxyribonuclease I)为类白色冷冻干燥粉末。溶于水，微溶于30％乙醇和丙酮。用于从蛋白质样品中除去DNA。

DNAse I is used to nick DNA, as a first step to incorporate labeled bases into DNA. The enzyme from Sigma has been used in the nuclease stock along with RNAse during cell lysate preparation of Madin-Darby canine kidney (MDCK) II cell lines. It has also been used during RNA extraction from Sindbis virus.

Deoxyribonuclease I from bovine pancreas has been used for the identification, localization and expression of two novel human genes similar to deoxyribonuclease I. Deoxyribonuclease I from bovine pancreas has also been used in a study to investigate a new approach to obtaining high-activity RNase, DNase, cholesterolesterase, and trypsin from cattle pancreas.

储存：冷冻（-20℃）。