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Corn Trypsin Inhibitor
货号：CTI | 规格：10 mg | 价格：￥0.00 | 品牌：Molecular Innovations
Corn Trypsin Inhibitor是由北京中昊新生科技有限公司提供，Molecular Innovations专注于凝血和溶栓试剂，包括PAI-446、tPA、尿激酶、凝血因子、玻连蛋白、纤维蛋白原、纤连蛋白、肾素原/肾素、前激肽释放酶、激肽释放酶、白蛋白、纤溶酶原、纤溶酶、抗纤溶酶、凝血酶、抗凝血酶、补体成分和免疫球蛋白。
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Corn Trypsin Inhibitor (CTI) is a highly specific inhibitor of trypsin and Factor XIIa that does not affect Factors VIIa, IXa, Xa, or thrombin. CTI forms a one-to-one molar complex with target proteases and is useful for distinguishing between the intrinsic and extrinsic coagulation cascades. CTI is extracted from high quality sweet corn meal into a physiologic buffer then purified by a combination of gel filtration, ion-exchange, and affinity chromatography. The final CTI preparation appears as a single band by SDS-PAGE analysis under both reducing and non-reducing conditions. Preparations of CTI are tested for the ability to prolong the aPTT assay without affecting the PT assay. The specific activity of each lot of CTI is determined, and one unit is defined as the amount of CTI required to double the aPTT of normal human plasma.
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