Recombinant human Factor beta-XIIa
货号：HFXIIAB-INS
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规格：0.05 mg
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价格：￥0.00
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品牌：Molecular Innovations
Recombinant human Factor beta-XIIa是由北京中昊新生科技有限公司提供，Molecular Innovations专注于凝血和溶栓试剂，包括PAI-817、tPA、尿激酶、凝血因子、玻连蛋白、纤维蛋白原、纤连蛋白、肾素原/肾素、前激肽释放酶、激肽释放酶、白蛋白、纤溶酶原、纤溶酶、抗纤溶酶、凝血酶、抗凝血酶、补体成分和免疫球蛋白。
The low molecular weight beta form of human Factor XIIa is generated in vivo by kallikrein cleavage of Factor alpha-XIIa and contains the catalytic light chain and the C-terminal peptide of the heavy chain of Factor alpha-XIIa. Recombinant Human Factor beta-XIIa is activated from insect cell culture derived Factor XII by an extended autoactivation process with Dextran Sulfate followed by repurification. Complete activation is observed on SDS-PAGE. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. Specific activity of this recombinant product is typically lower than that of plasma derived material. Custom mutants of Factor XII are also available, please contact us for more details.
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400-888-0207
