HIF1a抗体

描述:Goat polyclonal to alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in apoptosis, angiogenesis, energy metabolism, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in tumour angiogenesis, embryonic vascularization, and pathophysiology of ischemic disease.

别名:alpha subunit (basic helix-loop-helix transcription factor), ARNT interacting protein, basic-helix-loop-helix-PAS protein MOP1, bHLHe78, class E basic helix-loop-helix protein 78, HIF-1alpha, HIF1, HIF1-ALPHA, HIF1a, hypoxia inducible factor 1, hypoxia-inducible factor 1 alpha isoform I.3, hypoxia-inducible factor 1, hypoxia-inducible factor 1-alpha, member of PAS protein 1, member of PAS superfamily 1, MOP1, PASD8, PAS domain-containing protein 8 antibody.

浓度: 3 mg/ml

抗体类型: 一抗.

Target Name: Anti-HIF1a

Accession Number: ENSG00000100644

宿主: Goat

免疫原物种: Human

免疫原类型: Recombinant protein

免疫原: Purified recombinant peptide derived from within residues 470 to 590 aa of human HIF1a produced in E. coli.

亚型: IgG

克隆: Polyclonal

已确认的反应种属: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

特异性: Detects HIF1a in transfected cells and a band of approximately 120 kDa by Western blot in cell lysates.

储存缓冲液: PBS, 20% glycerol and 0.05% sodium azide

纯化: Epitope affinity purified

偶联物: Unconjugated

RRID: AB_2895328

经验证的应用: WB

推荐稀释: WB:1:500-1:2,000

储存条件: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.



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