HemogloBind™ Hemoglobin Removal and Captur

HemogloBind™ 从溶血血清/血浆中去除血红蛋白

HemogloBind™ 特点：

• 对血红蛋白具有高度特异性，不与其他蛋白或分析物发生交叉反应

• 应用于分析干扰，酶监测，蛋白质组学

• 样品物种不确定

• 众多引用文献，包括：cellular thermal shift assay (CETSA), LC-MS proteomics, Hemoglobin derivatives, Western blot, enzyme activity, ELISA

HemogloBind™ 适用于:

 ◦ 溶血血清/血浆

 ◦ 全血，干血卡（DBS）或红细胞裂解物

 ◦ 组织匀浆，与RIPA缓冲液兼容

HemogloBind™ 不与大多数常见的血清成分发生交叉反应，使其成为众多应用中的首选工具。其中包括有光学干扰问题的分析。

Poly-electrolytes are polymers with repeating units of stationary charges. HemogloBind™ is derived from insoluble elastomeric poly-electrolytes that bind proteins through an empirically derived chemistry combining elements of polymer composition, and cross-linking architecture. As with bio-polymers like DNA and Heparin, governing their reactivity is the spatial presentation of electrostatic groups along a flexible polymer chain.

HemogloBind™ does not cross react with most common serum components, making it an excellent tool in numerous applications. These include analytical protocols where optical interference is problematic. Hemoglobin variants, as in thalassemia, bind with differential affinity towards HemogloBind™, though this has not been fully evaluated. For purification and/or analysis of hemoglobin, a modest elevation in pH will facilitate desorption from the polymer.

HemogloBind™ 血红蛋白在血液中的去除性能
HemogloBind™ 血红蛋白在干血斑/干血卡上的去除性能


请参阅：
NuGel™ HemogloBind™干粉形式，与高通量96孔自动化兼容。