NuGel™ Poly-Carboxy

Non-specific sites are virtually eliminated by a polymer coating
Stable across a wide pH range 2 – 10
1000Å, 50µm Silica suitable for LC and batch processes
Applications include: Enzyme immobilization, separation and purification of biopolymers, immobilization of proteins & ligands – monoclonal antibodies, hormones, peptides, haptens, drugs, etc
Silica has been an industry standard as an advantageous matrix suitable for high performance liquid chromatography. With NuGel™, non-specific sites have been virtually eliminated making it an ideal support for affinity purification. Through a proprietary polymer coating, Silica is crosslinked forming a reactive Poly-Epoxy functionality stable across a wide pH range (pH 2 to 10). From this foundational chemistry, all of the NuGel™ affinity products are derived.

NuGel™ Poly-Carboxy Technical Data

NuGel™ Poly-Carboxy is a derivative of NuGel™ polyepoxy affinity support. This affinity support contains carboxy groups at the end of hydrophilic spacer arms and is used to couple ligands containing amino groups.

Special Features:

Couples ligands containing free amino groups in the presence of a carbodiimide.
Couples non-polar ligands in organic solvents.
pH stable from 2 to 9.

Special Features:
Covalently couples ligands containing free amino groups in the presence of a carbodiimide.
Covalently couples non-polar ligands in organic solvents.
pH stable from 2 to 9.