Murine Anti-Factor VIII抗体(GMA-8024)
货号：GMA-8024
|
规格：0.5 mg
|
价格：￥0.00
|
品牌：Greenmoab
Factor VIII抗体,Murine Anti-Factor VIII抗体(GMA-8024)推荐用于ELISA应用。
Factor VIII抗体
产品名称:
Murine Anti-Factor VIII抗体
Clone GMA-8024
描述:
Factor VIII (FVIII) is a heterodimer consisting of a heavy chain (ranging in mass from 90 to 200 kDa) bound via metal ions to a light chain (80 kDa). In plasma, FVIII circulates in an inactive form bound to von Willebrand factor. Following activation by factor Xa or thrombin, factor VIIIa can function as cofactor for the enzyme factor IXa in the activation of factor X in the presence of phospholipid and Ca2+ . Absent or defective FVIII is the cause of the X-linked recessive bleeding disorder hemophilia A. GMA-8024 (also known as 2-101) recognizes the A2 domain of FVIII and can be used in conjunction with GMA-8023 as a sandwich ELISA pair for detection of human FVIII. It does not bind murine, rhesus or cynomolgus FVIII.
物种反应性:
Human
来源:
Murine
特异性:
A2 domain
同型:
IgG1
应用
ELISA:
Binds the A2 domain of recombinant human factor VIII in solid-phase ELISA.
Immunoblotting:
Not recommended.
Inhibition:
Not inhibitory in aPTT clotting assay.
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