Deuterated Crosslinker DSP-d8
货号:h5104-10mg
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规格:10 mg
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价格:¥0.00
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品牌:ProteoChem
DSP-d8是由北京中昊新生科技有限公司提供.ProteoChem致力于蛋白生物化学和有机合成领域的生物试剂和化学试剂研发,生产NMR、质谱、蛋白偶联剂以及新型蛋白质组学试剂的分析标准品,用于质谱,药物研发,诊断和蛋白生物中的蛋白检测和蛋白修饰等方面。
DSP-d8 deuterated protein crosslinker, Dithiobis(succinimidyl 2,2,3,3,6,6,7,7-propionate-d8), is a cell membrane permeable, homobifunctional, protein crosslinker containing 8 deuterium atoms to provide an 8 Dalton shift by mass spectrometry compared to non-dueterated DSP (DSP-d0). DSP-d8 deuterated crosslinker has amine-reactive NHS esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm. DSP-d8 deuterated crosslinker contains a reducible disulfide bond (SS-bond) in the spacer arm that makes it a good choice for numerous applications where reversible crosslinking is desired.
Use the heavy DSP-d8 deuterated protein crosslinking reagent in combination with the light, non-deuterated analog (DSP-d0) for mass spec studies.
DSP-d8 deuterated crosslinker must be dissolved in an organic solvent, such as DMSO or DMF, and then may be added to an aqueous crosslinking reaction. Because DSP-d8 crosslinker is cell membrane permeable it can be used to crosslink intracellular proteins.
Molecular Weight: 412.46
Spacer Length: 12.0 Å
Alternative names: d 8 -DSP; DSP-d8; D8-DSP; Dithiobis(succinimidyl propionate-d8); DTSP-d8
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