Urinary Creatinine Assay Kit

DetectX® Urinary Creatinine Detection kit尿肌酐检测试剂盒用于定量测量尿液样本中的肌酐。NIST校准的肌酐标准品用于标准化检测。

检测类型:Detection Kit

样本类型:Urine

灵敏度:0.019 mg/dL

适应物种:Human, Rat, Dog, Monkey

检测时间:30 分钟

样品数/板:40 in Duplicate

读数:Colorimetric, 490 nm

如要测量血清或血浆样品中的肌酐，请参考DetectX®血清肌酐检测试剂盒，编号KB02-H1/KB02-H2或KB02-H1D。

检测原理:

The DetectX® Urinary Creatinine Detection Kit is designed to quantitatively measure creatinine present in urine samples of Human, Rat, Dog, and Monkey.  The Urinary Creatine Detection Kit can detect Creatinine in as little as 30 minutes. Please read the complete kit insert before performing this assay.

背景:

Creatinine (2-amino-1-methyl-5H-imidazol-4-one) is a metabolite of phosphocreatine (p-creatine), a molecule used as a store for high-energy phosphate that can be utilized by tissues for the production of ATP. Creatine comes from the diet or is synthesized from the amino acids arginine, glycine, and methionine. Synthesis mainly occurs in the kidneys and liver.

Creatine and p-creatine are converted non-enzymatically to the metabolite creatinine. Creatinine diffuses into the blood and is excreted by the kidneys. Creatinine forms spontaneously from p-creatine. Under normal conditions, its formation occurs at a rate that is relatively constant and as intra-individual variation is <15% from day to day, creatinine is a useful tool for normalizing the levels of other molecules found in urine. Altered creatinine levels may be associated with conditions such as diabetes and cardiovascular disease.

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