Garcinol,CAS:78824-30-3|中昊生物

Garcinol

货号：P017-25MG | 规格：25MG | 价格：￥0.00 | 品牌：Arbor Assays

Arbor Assays Garcinol,CAS:78824-30-3,强效组蛋白乙酰转移酶抑制剂,HATs p300和PCAF抑制剂,诱导HeLa细胞凋亡。
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特性:
Potent histone acetyltransferases inhibitor
Induces HeLa cell apoptosis
Anti-inflammatory and anti-carcinogenic
描述:
Garcinol is an inhibitor of the histone acetyltransferases (HATs) p300 and PCAF with IC50 of 7 and 5 uM, respectively. It also inhibits the HAT GCN5 in Cryptococcus neoformans, inducing temperature sensitivity and impairing growth. A polyisoprenylated benzophenone isolated from Garcinia indica, garcinol promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells. It induces apoptosis in several types of cancer cells and has anti-inflammatory actions.

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