HIF1a抗体
描述:Goat polyclonal to alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in apoptosis, angiogenesis, energy metabolism, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in tumour angiogenesis, embryonic vascularization, and pathophysiology of ischemic disease.
别名:alpha subunit (basic helix-loop-helix transcription factor), ARNT interacting protein, basic-helix-loop-helix-PAS protein MOP1, bHLHe78, class E basic helix-loop-helix protein 78, HIF-1alpha, HIF1, HIF1-ALPHA, HIF1a, hypoxia inducible factor 1, hypoxia-inducible factor 1 alpha isoform I.3, hypoxia-inducible factor 1, hypoxia-inducible factor 1-alpha, member of PAS protein 1, member of PAS superfamily 1, MOP1, PASD8, PAS domain-containing protein 8 antibody.
浓度: 3 mg/ml
抗体类型: 一抗.
Target Name: Anti-HIF1a
Accession Number: ENSG00000100644
宿主: Goat
免疫原物种: Human
免疫原类型: Recombinant protein
免疫原: Purified recombinant peptide derived from within residues 780 aa to the C-terminus of human HIF1a produced in E. coli.
亚型: IgG
克隆: Polyclonal
已确认的反应种属: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
特异性: Detects HIF1a in transfected cells and a band of approximately 120 kDa by Western blot in cell lysates.
储存缓冲液: PBS, 20% glycerol and 0.05% sodium azide
纯化: Epitope affinity purified
偶联物: Unconjugated
RRID: AB_2333145
经验证的应用: WB
推荐稀释: WB:1:500-1:2,000
储存条件: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
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