DMXAA
货号：P024-5MG
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规格：5MG
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价格：￥0.00
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品牌：Arbor Assays
Arbor Assays DMXAA/Vadimezan,CAS:117570-53-3,是一种对小鼠STING具有选择性的STING激动剂。
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DMXAA is a STING (Stimulator of Interferon Genes) agonist selective for mouse STING.
描述:
Intratumoral administration of DMXAA resulted in tumor regression and complete rejection in mouse xenografts. Tumor regression induced by DMXAA results from a cascade of cellular events which include disruption of tumor vasculature followed by the release of chemokines which trigger the recruitment of immune cells. DMXAA induced expression of IFN-β resulting in a striking expansion of leukemia-specific T cells extending survival in two acute myeloid leukemia models.
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