别孕烯醇酮ELISA试剂盒

DetectX®Allopregnanolone ELISA试剂盒用于检测各种样品中的Allopreganolone。

检测类型:

Competitive ELISA

样本类型:

Urine, Extracted Serum, Extracted Plasma (EDTA and Heparin), Dried Feces, Tissue Culture Media

灵敏度:

129.7 pg/mL

适应物种:

Allopregnanolone在不同物种间相同

检测时间:

2.5小时 or Overnight

样品数/板:

39 in Duplicate

读数:

Colorimetric, 450 nm

DetectX®别孕烯醇酮ELISA试剂盒提供有别孕烯醇酮标准品以生成测定的标准曲线，所有样品应从标准曲线中读出。将标准品或稀释的样品吸移到包被有抗体的微孔板中以捕获小鼠抗体。将别孕烯醇酮-过氧化物酶结合物添加到孔中，通过向每个孔中添加别孕烯醇酮单克隆抗体从而启动结合反应。

Allopregnanolone (3α-hydroxy-5α-pregnan-20-one, THP, THPROG) is a prototypic neurosteroid present in the blood and the brain. It is a metabolite of progesterone and potent modulator of GABAA receptors. Allopregnanolone has pharmacological properties including anxiolytic and anticonvulsant activity. The biosynthesis of allopregnanolone involves the conversion of progesterone into 5α-dihydroprogesterone by the enzyme 5α-reductase type I. Subsequently, 3α-hydroxysteroid oxidoreductase isoenzymes convert this intermediate into allopregnanolone. Anxiety and depression are common side effects of 5α-reductase inhibitors such as finasteride and dutasteride, and they are believed to be caused, in part, by the prevention of the endogenous production of allopregnanolone. Allopregnanolone aids neurogenesis and has been found to reverse neuron proliferative deficit and cognitive deficits in mouse models of Alzheimer’s disease.

Arbor Assays为临床重要生物分子研发最高质量的检测和免疫分析试剂盒,在生物领域建立健全的免疫检测和酶活性试剂盒以定量生物分子。Arbor Assays检测试剂盒具有高灵敏性,适用多物种及操作步骤简单的特点。

北京中昊新生科技作为美国Arbor Assays中国代理,一直为国内客户提供及时高效的配送和更专业的产品技术支持。为您提供Allopregnanolone ELISA Kit,别孕烯醇酮ELISA试剂盒最新现货优惠信息。