Resveratrol
货号:P002-500MG
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规格:500MG
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价格:¥0.00
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品牌:Arbor Assays
Arbor Assays Resveratrol,SIRT1激活剂,CAS:501-36-0,强效酚类抗氧化剂,环氧化酶-1(COX-1)选择性抑制剂。
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特性:
SIRT1 activator
Potent phenolic antioxidant
Selective inhibitor of cyclooxygenase-1
描述:
Potent SIRT1 activator and a phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC50 = 23 uM) and displays mixed agonist/antagonist actions at ERalpha and ERbeta estrogen receptors. Trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. trans-Resveratrol is also a selective inhibitor of cyclooxygenase-1 (COX-1). It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 uM, respectively. There is essentially no inhibition of the COX-2 activity. Resveratrol also activates sirtuins and, extends lifespan in C. elegans. Converted into the anticancer agent piceatannol by cytochrome P450 1B1.
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