SAHA (Vorinostat )
货号：P004-250MG
|
规格：250MG
|
价格：￥0.00
|
品牌：Arbor Assays
Arbor Assays SAHA(Vorinostat),CAS:149647-78-9,HDAC抑制剂,应用于皮肤T细胞淋巴瘤的治疗,体外和体内对潜伏性HIV感染T细胞影响的研究。
北京中昊新生是Arbor Assays中国代理商,我们很荣幸为您的研究提供产品订购以及帮您解决产品所有的技术问题。
特性:
HDAC inhibitor
Cutaneous T-cell lymphoma treatment
In vitro and in vivo effects on latent HIV infected T-Cells
Storage at room temperature
描述:
SAHA (suberoylanilide hydroxamic acid, Vorinostat, Zolinza™) is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. Sirt activator based on a dihydropyridine structural scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) is 1 uM for Sirt1, 25 uM for Sirt2, and 50 uM for Sirt3. The compound is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. SAHA inhibits class I and class II HDACs at around 50 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 uM.
相关产品
-
货号：P023-50MG
|
规格：50MG
|
价格：￥0.00
|
品牌：Arbor Assays
-
货号：P002-100MG
|
规格：100MG
|
价格：￥0.00
|
品牌：Arbor Assays
-
货号：P011-5MG
|
规格：5MG
|
价格：￥0.00
|
品牌：Arbor Assays
-
货号：P016-5MG
|
规格：5MG
|
价格：￥0.00
|
品牌：Arbor Assays
-
货号：P012-50MG
|
规格：50MG
|
价格：￥0.00
|
品牌：Arbor Assays
-
货号：P024-25MG
|
规格：25MG
|
价格：￥0.00
|
品牌：Arbor Assays
-
货号：P008-10MG
|
规格：10MG
|
价格：￥0.00
|
品牌：Arbor Assays
-
货号：P006-5MG
|
规格：5MG
|
价格：￥0.00
|
品牌：Arbor Assays
400-888-0207
