Apicidin
货号：P011-1MG
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规格：1MG
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价格：￥0.00
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品牌：Arbor Assays
Arbor Assays Apicidin/OSI 2040,CAS:183506-66-3,是强效HDAC抑制剂,阻断G1细胞周期,诱导HIV-1启动子的激活。
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特性:
Potent HDAC Inhibitor
Blocks Cell Cycle G1
HIV-1 Promoter
描述:
Potent inhibitor of histone deacetylase (HDAC) activity and proliferation. Induces cell cycle arrest at the G1 phase. At 100 nM it induces a long lasting hyperacetylation of histone H4 while that induced by trichostatin is transient. Stimulates apoptosis. Apoptosis is induced via induction of Fas/Fas ligand. Displays potent antiangiogenic effects and dramatically decreases HIF-1a protein levels and transcriptional activity in human and mouse tumor cell lines. Apicidin is a fungal toxin that has broad spectrum activity against Apicomplexan parasites.
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